| SBA |
- Small Business Administration |
| SDA |
- Service Delivery Area |
| SDP |
- Service Delivery Point |
| SDV |
- Special Disabled Veteran |
| SEC |
- Securities and Exchange Commission |
| SESA |
- State Employment Security Agency |
| SF |
- Standard Form |
| SGA |
- Solicitation For Grant Applications |
| SIC |
- Standard Industrial Classification |
| SIMPOC |
- Statistical Information and Monitoring Program |
| SOII |
- Survey of Occupational Injuries and Illnesses |
| SOL |
- Office of the Solicitor |
| SPIR |
- Standard Program Information Report |
| SQSP |
- State Quality Service Plan |
| SSA |
- Social Security Administration |
| STAWRS |
- Simplified Tax and Wage Reporting System |
| STW |
- School to Work |
| SWA |
- State Workforce Agency |